Using a device known as the Doppler fluxmeter, the experts were able to measure blood flow through the skin with a laser beam. When subjects were attached the device and give a solution containing hesperidin amount equivalent to two glasses of orange juice, the researchers found a decrease in blood pressure and improving the overall flow. When participants directly drank orange juice instead of hesperidin solution, their circulation was even better.

Experts note that for the measurement of the favorable effect of citrus fruits in the bloodstream does not always require special equipment. For example, in one study, researchers looked at the women who suffer from sensitivity to cold weather due to poor blood flow and often have cold hands and feet. One group of women drank a solution containing citrus phytonutrients, and the other (control) group received a placebo - orange flavored drink. Once placed in women cool room due to decreased blood flow fingertips their temperature fell by almost 13 degrees. At the same time the tips of fingers women who drank the real citrus juice, cooled to 2 times slower, because their blood flow remained more stable. When researchers loaded arm of the two groups of women in ice water, then the member receiving the compounds of citrus fruit, arms temperature recovered to 50% faster than the control group.