Researchers from Canada have learned to grow tissue outside the body
The uniqueness of the method lies in Chinese using microscopic three-dimensional arrays in which individual cells can be grown. Such artificial support let you receive the cells and tissues, which are more like real ones, than those grown in flat petri dish.
Mikroreshetki are of a biodegradable and biocompatible polymer POMaC and consist of a plurality of thin layers deposited patterns channel width from 50 to 100 microns. Layers that resemble in appearance computer microchips are collected into three-dimensional structures which are reproduced in synthetic blood vessels. As you add more layers they are irradiated with ultraviolet light, to connect with each other.
When construction is completed, it is immersed in a liquid containing living human cells. The cells quickly attached to the outside and the inside of the channel and begin to grow as they have done so within the human body.
With this technology, researchers from Toronto has managed to create a synthetic model of the heart and liver, which operate as living bodies. This artificial liver even capable of producing urea and processed drugs.
AngioChip has great potential in the field of pharmacological tests. Current methods of testing, including testing on animals and in a clinical setting, are very expensive and raises many ethical questions. Tests on tissue grown in the laboratory will allow to obtain a very realistic model for a very low price. This, in turn, will allow pharmaceutical companies to notice the dangerous side effects and interactions between the various bodies long before they come to market drugs that can save lives. In addition, AngioChip will allow to evaluate the effectiveness of existing drugs and to make libraries of chemical compounds to create new ones.
In the future, synthetic fabric can be implanted into the body to repair damaged organs. Since the donor cells may be the patient, grown tissue will be genetically identical to his own, which minimizes the risk of rejection.
AngioChip now ready to be implanted in the body tissues of animals. Artificial blood vessels effectively connected to the circulatory system of the body. Plastic lattice frame decompose without trace in a few months. Research involving human subjects has not yet been conducted.
Now a team from Toronto is working on the creation of industrial technology of its chips and looking for ways to commercialize the development.
Mikroreshetki are of a biodegradable and biocompatible polymer POMaC and consist of a plurality of thin layers deposited patterns channel width from 50 to 100 microns. Layers that resemble in appearance computer microchips are collected into three-dimensional structures which are reproduced in synthetic blood vessels. As you add more layers they are irradiated with ultraviolet light, to connect with each other.
When construction is completed, it is immersed in a liquid containing living human cells. The cells quickly attached to the outside and the inside of the channel and begin to grow as they have done so within the human body.
With this technology, researchers from Toronto has managed to create a synthetic model of the heart and liver, which operate as living bodies. This artificial liver even capable of producing urea and processed drugs.
AngioChip has great potential in the field of pharmacological tests. Current methods of testing, including testing on animals and in a clinical setting, are very expensive and raises many ethical questions. Tests on tissue grown in the laboratory will allow to obtain a very realistic model for a very low price. This, in turn, will allow pharmaceutical companies to notice the dangerous side effects and interactions between the various bodies long before they come to market drugs that can save lives. In addition, AngioChip will allow to evaluate the effectiveness of existing drugs and to make libraries of chemical compounds to create new ones.
In the future, synthetic fabric can be implanted into the body to repair damaged organs. Since the donor cells may be the patient, grown tissue will be genetically identical to his own, which minimizes the risk of rejection.
AngioChip now ready to be implanted in the body tissues of animals. Artificial blood vessels effectively connected to the circulatory system of the body. Plastic lattice frame decompose without trace in a few months. Research involving human subjects has not yet been conducted.
Now a team from Toronto is working on the creation of industrial technology of its chips and looking for ways to commercialize the development.